What Is Frozen Egg Donation

Frozen Egg Donation can be a highly successful treatment used for patients who no longer have high-quality eggs within their ovaries

Frozen Egg Donation” is an alternative to “fresh” (non-frozen) Egg Donation IVF treatment. Just like “fresh” Egg Donation, it can be a highly successful treatment for patients who no longer have sufficient quality eggs within their ovaries.

You choose your frozen donor eggs from a donor egg bank catalog. This is similar to choosing donor semen from a sperm bank.

Once you select the egg donor of your frozen eggs, the egg bank will ship your selected frozen eggs to our Clinic. The egg banks our embryologists recommend are Fairfax Egg Bank, Donor Egg Bank USA at California Cryobank, and Cryos International-USA.

Probability of Success: The likelihood of a successful pregnancy depends primarily on the fertility potential of the egg donor who provided your frozen donor eggs rather than your uterine receptivity or age.

The probability of a successful outcome with frozen donor eggs approaches the success of using “fresh” donor eggs.

Treatment Efficacy: We performed our first Egg Donation treatment in 1988. Since then, Donor Egg IVF has become a mainstream treatment for infertility. Over the years, we have streamlined and simplified the process of Donor Egg IVF to minimize interference with your egg donor’s lifestyle.

Frozen Donor Egg IVF Offspring: Children conceived with the help of Donor Egg IVF are genetically linked to the male partner and the egg donor, but the female partner is the one who becomes pregnant, nourishes the baby throughout the pregnancy, and experiences childbirth.

The baby receives one set of genes from the dad and another from an egg donor, but you, the mom carrying the pregnancy, make that baby your very own. The new science of epigenetics describes how our environment modifies gene expressions and possibly the genes themselves.

The epigenetic marks transmitted from the recipient mother are a fine-tuned mechanism to control gene activation during the complex process of early embryogenesis. And this maternal influence continues throughout the pregnancy. You will imprint yourself onto the baby! By the time your son or daughter is born, that baby will be biologically yours.

“Fresh” and Frozen Egg Donor IVF Comparison: In “fresh” Donor Egg IVF, the egg donor undergoes ovarian stimulation and egg retrieval. The eggs are inseminated with partner (or donor) sperm, and fertilized eggs are cultured in the laboratory. The resulting embryos are cryopreserved and subsequently transferred into the recipient mother’s uterus.

In Frozen Donor Egg IVF, the egg donor’s ovarian stimulation and egg retrieval have already taken place. The eggs have been vitrified (cryopreserved, frozen) by the egg bank. The cryopreserved eggs are shipped to Bay IVF, where they are thawed, inseminated, and the resulting embryos are frozen and subsequently transferred into the recipient mother’s uterus.

In both types of donor egg treatments, egg donors are tested for genetic and infectious diseases and are psychologically pre-screened.

Advantages of Frozen Donor Egg IVF: Frozen Donor Egg IVF may possibly be less costly than “fresh” Donor Egg IVF. The treatment length is shorter, and you may not need to decide what to do with extra embryos that might be left over after a successful “fresh” Donor Egg IVF treatment.

Advantages of “Fresh” Donor Egg IVF: “Fresh” Donor Egg IVF may have a higher success probability, and you may possibly have enough extra frozen embryos to improve your chances for a genetic sibling in the future.

Treatment Logistics: The rate of development of embryos from frozen donor eggs may be unpredictable, and it may not be possible to match the recipient’s uterine lining development with the development of the embryos.

This is resolved by thawing and inseminating the frozen donor eggs and freezing (vitrifying) the resulting embryos. The frozen embryos are thawed and transferred into the uterus in a subsequent Frozen Embryo Transfer.

Most embryos will survive the cryopreservation and thawing process. The implantation rate of the thawed embryos is equal to the “fresh” embryo implantation rate.

Obstetrical Care: Once your Frozen Embryo Transfer treatment at Bay IVF is completed (approximately 6-8 weeks into your pregnancy), your pregnancy will become indistinguishable from conception through intercourse, and your obstetrical care should be no different than if you conceived without any treatment.

Frozen Donor Egg IVF is a two-stage treatment. The first phase consists of the development and cryopreservation of embryos:

  1. Obtaining donor eggs from an egg bank
  2. Thawing of cryopreserved donor eggs
  3. Fertilization of eggs (Intracytoplasmic Sperm Injection – ICSI)
  4. Culture of embryos
  5. Cryopreservation of embryos
  6. Embryo storage

The second stage consists of the Frozen Embryo Transfer cycle.

Obtaining Donor Eggs from an Egg Bank: Once you have finalized the selection of your donor eggs, the egg bank will communicate with our Clinic, and our Embryology Laboratory will make preparations to receive your eggs. After their cryopreservation in the egg bank, eggs are stored and transported in liquid nitrogen containers. Once your eggs arrive at Bay IVF, they will be kept in liquid nitrogen storage until it is time to thaw them.

Thawing of Cryopreserved Donor Eggs: Since it is expected that not all cryopreserved eggs will survive the freezing-thawing process, and since not all thawed eggs will fertilize or develop into healthy embryos, you will be purchasing a cohort of eggs. You should expect to receive between 5 and 8 vitrified eggs from the egg bank.

Such a cohort will likely produce some good-quality embryos suitable for transfer.

Fertilization of Eggs: The male partner collects a semen specimen by masturbation on the day of thawing the eggs. The highest quality sperm are extracted from the semen, and Intracytoplasmic Sperm Injection (ICSI) is performed. In ICSI, a single sperm is inserted into an egg. ICSI is necessary for the fertilization of cryopreserved eggs.

Culture of Embryos: Evidence of fertilization can be seen the next day, 16 hours after ICSI. The fertilized eggs are transferred into a growth medium and continue to be cultured in our laboratory.

A normally fertilized egg (zygote) will show two pronuclei representing the genetic material from the egg and sperm.

The following day, embryos should divide into 4 cells, and the day after that, into 8 cells.

This picture shows a morphologically exquisite, day three, 8-cell embryo. Human embryos are still microscopic and invisible to the naked eye at this stage.

By the fifth to seventh day after the insemination, embryos should reach the blastocyst stage (80 or more cells).

This picture shows an advanced stage of blastocyst development. Notice the central fluid-filled cavity. The cells within the blastocyst have already differentiated into the inner cell mass (at seven o’clock) that will give rise to the fetus and the trophectoderm cells that will form the future placenta.

Cryopreservation of Embryos: Embryos that develop normally are cryopreserved. Preparation for the freezing process involves removing water from within the embryos and replacing it with a cryoprotective substance to prevent ice crystal formation during vitrification and subsequent thawing. The embryos are then flash-cooled to -196°C (-321°F). Such rapid freezing (vitrification) prevents damaging water crystal formation.

Embryo Storage: Following the vitrification process, the embryos are transferred into a liquid nitrogen storage chamber in our Clinic. Theoretically, there is no limit on the length of storage, but conceiving past the age of 40 may result in a high-risk pregnancy.

Once you decide to conceive with your cryopreserved embryos, you will have one or two embryos thawed and transferred into your uterus. A large majority of the embryos will survive the vitrification and thawing process. The implantation rate of the thawed embryos should be the same.

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We look forward to meeting you at Bay IVF and, when your treatment is successful, celebrating your new pregnancy!


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Compassionate Care

Hear from Our Patients’ Journey to Parenthood at Bay IVF!

I would highly recommend Bay IVF for those wanting to build their family and needing IVF support! Dr. Polansky and the whole Bay IVF team were so supportive and welcoming while also honest and realistic. Our girl is our dream come true!

Jennifer C.-F.

This clinic has been amazing to work with. All the nurses and staff made sure I was always comfortable and were there to answer questions any time I needed. We are incredibly grateful to Dr. Polansky and the team for everything they did for us.

Harpreet K.

Words could never express the gratitude my husband and I will always have for Bay IVF! We did our research and decided to check out Bay IVF. We scheduled a consultation and felt an instant connection… love at first sight!

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Meet Your Doctor

  • Dr. Polansky received his medical diploma from Charles University in Prague, the Czech Republic, in 1978.
  • After completing his OB/GYN residency at Jewish Hospital in Saint Louis, MO, he graduated from the Reproductive Endocrinology and Infertility (REI) fellowship at Stanford University in 1985.
  • In the same year, he co-founded the Stanford IVF Clinic.
  • Dr. Polansky obtained board certification in Obstetrics and Gynecology in 1986 and became REI subspecialty board certified in 1988.
  • In 1987, he left Stanford University and established Nova IVF.
  • In 2011, he founded Bay IVF, where he provides advanced fertility treatments with a holistic approach, utilizing state-of-the-art techniques.
  • Dr. Polansky personally performs ultrasound examinations, egg retrievals, embryo transfers, and ovarian and endometrial stimulations for his patients.
  • He is deeply committed to his patients and freely shares his cell phone number, ensuring accessibility and availability 24/7.

Frank Polansky, M.D.

Dr. Polansky’s Communication With Patients

Real texts, anonymous patient names

Initial Appointment Questions

When you call to schedule your consultation, Erica will ask you a short series of questions regarding your reproductive history.

  • Your name
  • Your date of birth
  • Your height
  • Your weight
  • Do you know which treatment you plan to have?
  • How many times have you been pregnant?
  • For each of your pregnancies, what was the conception date? (month and year)
  • What was the outcome?
  • Were the pregnancies with your current partner?
  • If known, what is the cause of your infertility?
  • What is your average cycle length? (number of days between onsets of your periods)
  • Are you currently taking any medications? If yes, which ones?
  • Are you allergic to any medications? If yes, which ones?
  • Your partner’s name (if applicable)
  • Your partner’s date of birth (if applicable)
  • What is the length of your relationship with your current partner? (years and months)
  • When was the last time either of you used any contraception?
  • Is the male partner currently taking any medications? If yes, which ones?
  • Is the male partner allergic to any medications? If yes, which ones?
  • What is the total number of pregnancies the male partner has ever caused?
  • Has the male partner ever caused a pregnancy without the ICSI (Intracytoplasmic Sperm Injection) procedure?
  • Has the male partner had a vasectomy or vasectomy reversal?
  • If available, for each Semen Analysis, please give the date (day, month, and year), volume, concentration (sperm count), percentage of motile sperm, and percentage of morphologically normal sperm.
  • Have you ever had any treatment for, or problems with, your lungs, heart, blood and blood vessels, breasts, digestive system, genito-urinary system, thyroid disease, diabetes, or neurological disorder? (female partner only)
  • For each X-ray of your uterus and Fallopian tubes (hysterosalpingogram), laparoscopy, hysteroscopy, or laparotomy, please give the procedure date (day, month, and year) and the findings.
  • If available, for each FSH, LH, estradiol (estrogen, E2), and AMH (Anti-Mullerian Hormone) test you have had, please give the date of the test (day, month, and year) and the result.
  • Have you done any intrauterine inseminations (IUI)? If yes, how many?
  • Have you had ovarian stimulation with injectable medications?
  • For each IVF treatment you have had, please provide the following information if available: Date (month and year), the dose of medications to stimulate your ovaries, your highest estrogen level, number of ovarian follicles that developed, number of eggs retrieved, whether ICSI was done, number of embryos available, number of embryos transferred, number of embryos frozen, and the treatment outcome.
  • Have you ever smoked cigarettes? If yes, how many cigarettes a day during the last three months? (Please remember that you must not smoke during your treatment.)

This is Erica

She will be providing you with exceptional support throughout your treatment journey at Bay IVF.

Listen to a typical conversation between Erica and a new patient.

Patients’ Thank You Cards

Your Initial Visit at Bay IVF

Attending a new patient appointment at a fertility clinic can be stressful. Our primary objective is to ensure that your initial visit is friendly and relaxing. We encourage you to ask questions at every step of the process.

1 — When You Arrive

You will be welcomed by one of the clinic receptionists. One of our nurses will measure your height and weight and take your blood pressure

2 — Meet Your Doctor

Dr. Polansky will ask you a series of clarifying questions and then provide you with a summary of the factors contributing to your infertility

4 — Exam Room

One of the nurses will escort you to an examination room. Your examination will begin with listening to your lungs and heart

3 — Ask Your Questions

You will then have a discussion with him about the most suitable reproductive treatment(s) for you. During this time, you will have the opportunity to ask any questions you may have

5 — Ultrasound of the Ovaries

The next step is a pelvic ultrasound to examine the uterus and ovaries. This ultrasound will help determine the number of antral follicles present within the ovaries

6 — Financial Part

Following that, you will have a discussion with one of the financial advisors regarding the financial aspects of your treatment, including potential treatment financing options

8 — Support 24/7

If you have any questions after leaving the clinic, please feel free to reach out to us via phone call, text, or email. Open and discreet communication is an integral part of the care we provide at Bay IVF

7 — What About Time?

Your entire visit is expected to last approximately one hour

Schedule Your Initial Consultation With Dr. Polansky

Online or In-Person

You can also complete the form below to request your initial consultation

    Next Step: One of our coordinators will call you for information about your reproductive history. See the questions they will ask on Our First Phone Call

    Still Have Questions?

    We know this is a big decision. It is important for us that you feel really comfortable.